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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BECN1
All Species:
43.03
Human Site:
Y229
Identified Species:
63.11
UniProt:
Q14457
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14457
NP_003757.1
450
51896
Y229
L
D
Q
E
E
A
Q
Y
Q
R
E
Y
S
E
F
Chimpanzee
Pan troglodytes
XP_511522
450
51866
Y229
L
D
Q
E
E
A
Q
Y
Q
R
E
Y
S
E
F
Rhesus Macaque
Macaca mulatta
XP_001111932
450
51890
Y229
L
D
Q
E
E
A
Q
Y
Q
R
E
Y
S
E
F
Dog
Lupus familis
XP_537634
362
42279
N164
D
E
L
K
S
V
E
N
Q
M
R
Y
A
Q
M
Cat
Felis silvestris
Mouse
Mus musculus
O88597
448
51515
Y227
L
D
Q
E
E
A
Q
Y
H
R
E
Y
S
E
F
Rat
Rattus norvegicus
Q91XJ1
448
51538
Y227
L
D
Q
E
E
A
Q
Y
Q
R
E
Y
S
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514527
394
45783
V194
L
D
D
E
L
K
S
V
D
N
Q
M
R
Y
A
Chicken
Gallus gallus
Q5ZKS6
447
51416
Y226
L
E
Q
E
E
A
Q
Y
Q
K
E
Y
C
E
F
Frog
Xenopus laevis
Q6GP52
445
51275
Y224
L
E
Q
E
E
A
R
Y
Q
K
E
Y
S
E
F
Zebra Danio
Brachydanio rerio
P13104
284
32704
V85
A
T
D
A
E
G
D
V
A
S
L
N
R
R
I
Tiger Blowfish
Takifugu rubipres
NP_001032963
447
51199
Y226
L
D
T
E
E
L
Q
Y
Q
K
E
Y
S
E
F
Fruit Fly
Dros. melanogaster
Q9VCE1
422
48852
Y205
L
H
E
Q
E
E
S
Y
W
R
E
Y
T
K
H
Honey Bee
Apis mellifera
XP_392365
430
49618
Y209
L
Q
S
E
E
E
R
Y
W
K
E
Y
S
K
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786368
415
47747
Y198
L
K
L
E
E
E
R
Y
W
Q
E
Y
N
E
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M367
517
58486
Y266
F
N
E
L
E
D
R
Y
W
Q
E
F
N
N
F
Baker's Yeast
Sacchar. cerevisiae
Q02948
557
63242
K282
L
E
N
E
K
L
Q
K
L
S
D
Q
N
L
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.7
78.8
N.A.
97.3
97.3
N.A.
76.8
91.7
88.6
20
81.1
49.1
56.4
N.A.
57.5
Protein Similarity:
100
99.7
99.7
79.5
N.A.
98
98.2
N.A.
81.5
94.6
94.8
36.4
89.5
67.7
69.3
N.A.
71.5
P-Site Identity:
100
100
100
13.3
N.A.
93.3
100
N.A.
20
80
80
6.6
80
40
46.6
N.A.
46.6
P-Site Similarity:
100
100
100
46.6
N.A.
93.3
100
N.A.
26.6
93.3
100
6.6
86.6
66.6
66.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
28
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.2
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
44
0
0
7
0
0
0
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
7
44
13
0
0
7
7
0
7
0
7
0
0
0
0
% D
% Glu:
0
25
13
75
82
19
7
0
0
0
75
0
0
57
0
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
57
% F
% Gly:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% G
% His:
0
7
0
0
0
0
0
0
7
0
0
0
0
0
13
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% I
% Lys:
0
7
0
7
7
7
0
7
0
25
0
0
0
13
0
% K
% Leu:
82
0
13
7
7
13
0
0
7
0
7
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
13
% M
% Asn:
0
7
7
0
0
0
0
7
0
7
0
7
19
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
44
7
0
0
50
0
50
13
7
7
0
7
0
% Q
% Arg:
0
0
0
0
0
0
25
0
0
38
7
0
13
7
0
% R
% Ser:
0
0
7
0
7
0
13
0
0
13
0
0
50
0
0
% S
% Thr:
0
7
7
0
0
0
0
0
0
0
0
0
7
0
0
% T
% Val:
0
0
0
0
0
7
0
13
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
75
0
0
0
75
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _